Job Summary

Drexel University, School of Biomedical Engineering, Science and Health Systems, Huang Lab is seeking a highly motivated Postdoctoral Scholar to join its interdisciplinary team focused on developing a next-generation cell expansion platform (CAREp) to address current limitations in CAR-T cell manufacturing. The successful candidate will contribute to translational research efforts aimed at enhancing both autologous and allogeneic CAR-T manufacturing workflows through precision biomaterials, with applications in oncology and autoimmune diseases.

Essential Functions

• Design and conduct in vitro T cell expansion assays using CAREp microsphere stimulation. 
• Optimize CAR-T expansion protocols from primary human T cells (including patient-derived and donor cells). 
• Perform phenotypic and functional characterization (flow cytometry, scRNA-seq, cytotoxicity, mitochondrial fitness). 
• Collaborate with internal and external partners on CAR constructs and allogeneic editing (e.g., CRISPR). 
• Prepare research manuscripts, contribute to grant applications, and present findings at meetings.
• Adhere to laboratory safety, ethics, and data integrity standards. 

Required Documents

• Minimum of PhD or Doctorate in PhD in Immunology, Bioengineering, Cell Biology, or related field.
• Strong skills in confocal imaging, molecular biology, and functional immune assays.
• Familiarity with biomaterials or polymer synthesis is a plus.
  
  

Preferred Qualifications

• Excellent communication and teamwork abilities.
• Experience with T cell culture, CAR-T systems, or immunotherapy is preferred.

Physical Demands

• Typically sitting at a desk/table
• Typically standing, walking
• Typically bending, crouching, stooping

Location

• University City - Philadelphia, PA

Additional Information
This position is classified as Exempt, grade K. Compensation for this grade ranges from $54,630.00 - $81,940.00. Please note that the offered rate for this position typically aligns with the minimum to midrange of this grade, but it can vary based on the successful candidate’s qualifications and experience, department budget, and an internal equity review.

Applicants are encouraged to explore the Professional Staff salary structure and Compensation Guidelines & Policies for more details on Drexel’s compensation framework. For information about benefits, please review Drexel’s Benefits Brochure.

Special Instructions to the Applicant
Please make sure you upload your CV/resume and cover letter when submitting your application.

A review of applicants will begin once a suitable candidate pool is identified.